Quinoa (Chenopodium quinoa Willd.) is a valuable medicinal plant well-known for its exceptional nutritional properties and resistance to adverse environmental conditions due to its unique phytochemical compounds. Quinoa seed with 15% proteins and high quality of amino acid composition has been considered as a perfect food, and also a valuable source for vitamins, minerals and bioactive compounds such as polyphenols, phytosterols, and flavonoids. A single serving (40 g/day) of quinoa would deliver a large portion of Recommended Daily Allowance (RDA) of key nutrients and health-beneficial compounds to the consumer. According to FAO/WHO recommendations, quinoa protein can supply over 180% of the daily recommended intake of essential amino acids for adult nutrition with proper ratio of histidine, isoleucine, leucine, lysine, methionine, phenylalanine, threonine, tryptophan, tyrosine, and valine. Accordingly, quinoa seed can be introduced as nutriceutical composition for billions of human under malnutrition and pharmaceuitical shortage on the world and because of that, 2013 was named as quinoa year by FAO. In this comprehensive paper it isaimedto introduce functional properties of quinoa and its advance in grank in food biosafety.