Improper use of soil resources leads to reduced fertility and soil degradation, and ultimately reduced crop production. Chemical fertilizers are a very strong competitor to biofertilizers because they are cheaper, easier to access, and faster return on investment. Accordingly, the aim of this study was conducted to evaluate the rhizosphere bacteria that stimulate plant growth and provide biosecurity with the approach of modifying the root structure of plants. The study showed that the rhizosphere supports the development and activity of a large and diverse community of microbial organisms, including organisms in plant growth, which can be used in the biological control of plant diseases. Bacillus sp. and Pseudomonas sp. It also causes an increase in all biological diseases. These microorganisms are investigated in the present study. Findings showed that reducing production costs on a large scale is a difficult task but can be achieved with careful research. In addition, the analysis of the benefits, risks, and limitations of the use of Rhizobacteria requires a more comprehensive and detailed investigation. Because the choice of appropriate method of plant disease control is based on balance.