TY - JOUR JF - Journal-of-Biosafety JO - VL - 11 IS - 2 PY - 2019 Y1 - 2019/1/01 TI - Antimicrobial Peptides an Important Factor Biosafety of Multicellular Organisms TT - پپتیدهای ضدمیکروبی عامل مهم ایمنی زیستی در موجودات زنده چند سلولی N2 - Multicellular organisms live, by and large, harmoniously with microbes. The cornea of the eye of an animal is almost always free of signs of infection. The insect flourishes without lymphocytes or antibodies. A plant seed germinates successfully in the midst of soil microbes. How is this accomplished? Both animals and plants possess potent, broad-spectrum antimicrobial peptides, which they use to fend off a wide range of microbes, including bacteria, fungi, viruses and protozoa. What sorts of molecules are they? How are they employed by animals in their defence? As our need for new antibiotics becomes more pressing, could we design anti-infective drugs based on the design principles these molecules teach us? SP - 83 EP - 109 AU - jabaleh, isa AU - kazzazi, majid AU - asoodeh, ahmad AD - Assistant Professor Department of Plant Protection, College of Agriculture, Bu–Ali Sina University, Hamedan, Iran. KW - Antibiotic KW - Epithelia KW - Insects KW - Plants KW - Vertebrates UR - http://journalofbiosafety.ir/article-1-250-en.html ER -