The number of people suffering from infectious, inflammatory and bone diseases is increasing every year. Producing of pharmaceutical proteins by extracting from human and animal tissues by using the traditional ways not only has a lot of disadvantages, but cannot supply increasingly demands as well. The demands for those pharmaceuticals available in the market and new ones will remarkably grow in the future, so great efforts are being made to find alternative approaches to produce pharmaceutical proteins, and one of them is biofarming. In this method, genetically engineered plants and animals are used to produce pharmaceuticals. Nowadays, plants have been given special attention for producing pharmaceutical proteins. Bone morphogenetic protein (BMP), a biological active drug, has a growing market. This protein is used in spinal surgery, bone fracture, jaw surgery and root canal, as well as bone tissue regeneration. Various systems are currently being used to generate BMP. Due to increasingly demand for BMP, there is seemingly a need to find a cheaper alternative way to mass produce it, which using transgenic plants is one of them rather than other expression systems. Here, the benefits of producing biological pharmaceuticals in plants and high economic efficiency of this sort of producing, and the use of BMP are reviewed.