Assistant Professor of Shahrekord University, Department of Biology
Abstract: (3390 Views)
Cytokines are protein or glycoprotein components that play an important role in inflammation and its regulation. Pro-inflammatory and anti-inflammatory cytokines are two groups of these components in which a dynamic equilibrium is essential to keep the body homeostasis. In the autoinflammatory disease pathology, it has been revealed that the balance between these components is disrupted and shifted to the pro-inflammatory cytokines. Therefore, using anti-inflammatory cytokines is one of the best method for inhibition of the inflammation and treatment for these diseases. In this review, study cytokines and methods of their inhibition were mentioned. This study showed that there are five general methods for the inhibition of pro-inflammatory cytokines, which are used in the treatment of some diseases. It is believed that the use of these methods can open the doors of a new way for treatment of autoinflammatory diseases.