Although Genetically Modified (GM (plants are cultivated on more than 180 million hectares, but considerations has been raised about them. Available impact studies GM crops show that these technologies are beneficial to farmers and consumers, producing large gains as well as positive effects for the environment and human health. Increased production of GM crops could significantly contribute to global food security and poverty reduction. However, widespread concerns about transgenic plants create a complex system of regulations that lead to a real threat to the increase of development and usage of the genetically modified product. GM technology has been part of the agricultural landscape for more than 20 years and has now been adopted on in both developed countries (47%) and developing countries (53%). In the past year, the direct global farm income benefit from GM crops was $17.7 billion and since 1996, farm incomes have increased by $150.3 billion. This article reviews the existing literature on cultivation and economic evaluation of transgenic plants by focusing on the global market of biotech crops has been discussed since 1996.