Plant diseases caused by viruses are a serious threat to the world's agricultural production, and anti-virus engineering, initiated by molecular biotechnology, is an effective strategy for preventing and controlling plant-borne viruses. Recent advances in targeted DNA or RNA editing with a short palindromic replication system or CRISPR-related are attractive tools that can be used to protect plants. In this review, the development of CRISPR/Cas systems is surved and their programs in controlling various plant viruses by targeting viral sequences or susceptibility genes in the host are mentioned. In addition, it introduces some potentially recessive resistance genes that can be used to improve plants against viruses, and emphasizes the importance of recessive gene-based antiviral modification for producing plants free of virus and growth deficiency. In addition, the challenges and opportunities of using CRISPR/Cas techniques in the prevention and control of plant viruses are discussed.