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Bioinformatics analysis of pcbAB, pcbC and penDE genes in penicillin synthesis at fungi
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Fatemeh Miri *   , Mohammad ali Tajick ghanbari , Heshmatallah Rahimian , Ghorbanali Nematzadeh |
| Plant Pathology, Agricultural Sciences and Natural Resources, University of Sari, Sari, Iran |
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Abstract: (3699 Views) |
| Antibiotics are valuable components that are being used for human health globally. Fungi, bacteria are such important antibiotic producers. At the recent survey we have collected the DNA sequences of several fungal genera, penicillin antibiotic related genes (penDE, pcbC, pcbAB) from databanks and clustered by MEGA5 software. A sequence comparison represents considerable similarities and differences at several levels, it could be considered as placement of each gene at different clade, sequence similaritiesbetween Penicillium and Aspergillus genera andbetween A. flavus and A. oryzae and also P. chrysogenum and P. nalgiovence. According to the importance of the antibiotics specially penicillin, it seems these similarities and differences could be a best candidate for the subsequent bioinformatics researches. |
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| Keywords: Antibiotic, Phylogenetic analysis, MEGA5, Penicillium, Aspergillus |
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Full-Text [PDF 355 kb]
(769 Downloads)
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Type of Study: Research |
Subject:
Special
Received: 2014/10/27 | Accepted: 2019/02/23 | Published: 2019/02/23
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